PD Dr. med. Klaus Tiemann

1989 – 1996         Studium der Humanmedizin an der Rh. Friedrich-Wilhelms Universität Bonn

1996                    Ärztliche Prüfung (Staatsexamen) und USMLE I u. II

1994 – 1996         Dissertation (summa cum laude, Promotionspreis der Universität, Bonn)

1996 – 1997        Post-Doc: Medizinische Poliklinik Bonn / Fraunhofer-Institut für Biomedizinische Technik St. Ingbert: Entwicklung eines neuen auf der Messung der Doppler-Power basierenden Messalgorithmus zur Durchblutungsmessung in kleinlumigen Blutgefäßen

1997                    Approbation als Arzt

1997-2001           Wiss. Mitarbeiter Medizinische Klinik II, Universitätsklinikum Bonn      
(Direktor Prof. Dr. med. Dr. h.c. B. Lüderitz)

2001-2003           Wiss. Assistent (C1)

2001                    Stipendium BONFOR

2003                    Facharzt für Innere Medizin

Seit 2004             Oberarzt der Medizinischen Klinik II (C2) des UKB: Leitung Echokardiographie-Labor u. Kardiale Bildgebung, Leiter EMAH-Ambulanz, OA-Rotation (div. Kardiologische Stationen (NA, Intensiv, Wach- u-Normalstation) und 24h Katheterbereitschaft

2004                    Habilitation und venia legendi für Innere Medizin
                              Schwerpunktsbezeichnung Kardiologie

2008-2011           Universitätsprofessur für Kardiovaskuläre Bildgebung am UK- Münster (Med. Klinik C), Westfälische Wilhelms-Universität Münster, Leiter Cardiac Imaging Center am UKM

2012                    DEGUM Kursleiter Echokardiographie Stufe 3

2011 – 2015         CA der Klinik für Kardiologie und Internistische Intensivmedizin Isar-Klinikum München

20215                  Umhabilitation Technische Universität München

seit 2015             CA Klinik für Kardiologie und Internistische Intensivmedizin, Peter Osypka Herzzentrum, München

2018                   DGK  Zusatzqualifikation CT Stufe 3

seit 1998             seit 1999 Mitglied der Dt. Gesellschaft für Kardiologie

seit 1998             Member of the European Association of Echocardiography

seit 1999             Mitglied der AG kardiovaskulärer Ultraschall der DGK

seit 2000             Editorial board der Fachzeitschrift “Echocardiography”

seit 2000             Member of the American Society of Echocardiography

2002 – 2015        Nukleusmitglied der Arbeitsgruppe AG-05 DKG

seit 2002             Associate Editor der Fachzeitschrift „Echocardiography“

seit 2003             Editorial board der Fachzeitschrift “International Journal of Cardiovascular Imaging”

2004-2018           International Society of Cardiovascular Ultrasound (Faculty)

seit 2007             Senior Associate Editor der Fachzeitschrift “Echocardiography”

2011 – 2015        Sprecher der AG Echokardiographie der DGK

2012 – 2016        Sprecher Deutsche Gesellschaft für Ultraschall in der Medizin – AK Echo

2015 -2018         Sprecher Cluster Kardiovaskuläre Bildgebung der DGK

seit 2016             Mitglied der Akademie für Aus- und Weiter- und Fortbildung der DGK

seit 2017             Mitglied Ausschuss Zertifizierung der DGK

seit 2021             Editor in Chief Journal “Echocardiography” (Wiley)

Curriculum KardiologieK Werdan, J Bauersachs, H Baumgartner, CM Bongarth, M Buerke, …
Der Kardiologe, 1-2892020 Virtual Reality Analysis of Three-Dimensional Echocardiographic and Cardiac Computed Tomographic Data SetsA Narang, N Hitschrich, V Mor-Avi, M Schreckenberg, G Schummers, …
Journal of the American Society of Echocardiography 33 (11), 1306-1315 2020

Proximal myopathy and fulminant heart failure in a 57 year-old female patient with lupus erythematosusF Wille, S Birkmeier, K Tiemann, T Lewalter, K Klingel, C Rabe, P Sick Der Internist 61, 854-859 2020

Manual zur Indikation und Durchführung der Echokardiographie–Update 2020 der Deutschen Gesellschaft für KardiologieA Hagendorff, W Fehske, FA Flachskampf, A Helfen, Felix Kreidel, Sebastian Kruck, Karl La Rosée, Klaus Tiemann, Jens-Uwe Voigt, Ralph Stephan von Bardeleben, Ralf Zahn, Fabian Knebel. Der Kardiologe, 1-34 2020

Structured reporting in cross-sectional imaging of the heart: reporting templates for CMR imaging of cardiomyopathies (myocarditis, dilated cardiomyopathy, hypertrophic …AC Bunck, B Baeßler, C Ritter, JR Kröger, T Persigehl, DP Santos, Michael Steinmetz, Adelheid Niehaus, Fabian Bamberg, Meinrad Beer, Sebastian Ley, Klaus Tiemann, Philipp Beerbaum, David Maintz, Joachim Lotz. RöFo-Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden …2020

Strukturierte Befundung in der Schnittbilddiagnostik des Herzens: Befundvorlagen für die MRT bei Kardiomyopathien (Myokarditis, dilatative Kardiomyopathie, hypertrophe …AC Bunck, B Baeßler, C Ritter, JR Kröger, T Persigehl, DP Santos, Michael Steinmetz, Adelheid Niehaus, Fabian Bamberg, Meinrad Beer, Sebastian Ley, Klaus Tiemann, Philipp Beerbaum, David Maintz, Joachim Lotz. RöFo-Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden … 2020

Preparation of PCI Balloons: What Is the Best Method to Avoid Air in the Balloon? A Comparison of Different Methods of Connecting PCI Balloons and the Inflation Syringe while …L Kreuser, KL Laugwitz, K Tiemann, T Lewalter, C Jilek Journal of clinical medicine 9 (1), 172 2020

3D Printing of Patient-Specific Mitral Valve Replicas from Echocardiography for Pre-operative Surgical PlanningM Kruttschnitt, K Tiemann, N Hitschrich, TC Lueth, R Sodian Innovative Surgical Sciences 2020

Manual on indications and performance of echocardiography-Update 2020 of the German Cardiac SocietyA Hagendorff, W Fehske, FA Flachskampf, A Helfen, F Kreidel, S Kruck, Karl La Rosee, Klaus Tiemann, Jens-Uwe Voigt, Ralph Stephan von Bardeleben, Ralf Zahn, Fabian Knebel Kardiologe 2020

Patient-specific subvalvular apparatuses consisting of chordae tendineae and papillary muscles to complete mitral valve replicasM Kruttschnitt, F Rehfuess, K Tiemann, N Hitschrich, R Sodian, TC Lueth
2019 IEEE International Conference on Robotics and Biomimetics (ROBIO), 1538 …2019

Patient-specific mitral valve replicas for preoperative planning of mitral valve repairM Kruttschnitt, NN Hassan, K Tiemann, N Hitschrich, R Sodian, TC Lueth ASME International Mechanical Engineering Congress and Exposition 59407 … 2019

Percutaneous left atrial appendage occlusion: the Munich consensus document on definitions, endpoints, and data collection requirements for clinical studiesA Tzikas, DR Holmes, S Gafoor, CE Ruiz, C Blomström-Lundqvist, Hans-Christoph Diener, Riccardo Cappato, Saibal Kar, Randal J Lee, Robert A Byrne, Reda Ibrahim, Dhanunjaya Lakkireddy, Osama I Soliman, Michael Nabauer, Steffen Schneider, Johannes Brachmann, Jeffrey L Saver, Klaus Tiemann, Horst Sievert, A John Camm, Thorsten Lewalter
Ep Europace 19 (1), 4-15 151 2017

Imaging reveals the connection between spontaneous coronary plaque ruptures, atherothrombosis, and myocardial infarctions in HypoE/SRBI−/− miceS Hermann, MT Kuhlmann, A Starsichova, S Eligehausen, K Schäfers, Jörg Stypmann, Klaus Tiemann, Bodo Levkau, Michael Schäfers Journal of Nuclear Medicine 57 (9), 1420-1427 2016

A planning system of the implant size and position for minimally-invasive closure of the left atrial appendageEC Graf, K Tiemann, J Praceus, TC Lueth 2016 6th IEEE International Conference on Biomedical Robotics and …2016

Sphingosine‐1‐Phosphate Receptor 1 Regulates Cardiac Function by Modulating Ca2+Sensitivity and Na+/H+ Exchange and Mediates Protection by Ischemic …P Keul, MMGJ van Borren, A Ghanem, FU Müller, A Baartscheer, Arie O Verkerk, Frank Stümpel, Jan Sebastian Schulte, Nazha Hamdani, Wolfgang A Linke, Pieter van Loenen, Marek Matus, Wilhelm Schmitz, Jörg Stypmann, Klaus Tiemann, Jan‐Hindrik Ravesloot, Astrid E Alewijnse, Sven Hermann, Léon JA Spijkers, Karl‐Heinz Hiller, Deron Herr, Gerd Heusch, Michael Schäfers, Stephan LM Peters, Jerold Chun, Bodo Levkau
Journal of the American Heart Association 5 (5), e003393 2016

Renal contrast‐enhanced sonography findings in a model of acute cellular allograft rejectionA Grabner, D Kentrup, H Pawelski, M Mühlmeister, C Biermann, B Edemir, V Van Marck, T Bettinger, H Pavenstädt, E Schlatter, J Stypmann, K Tiemann, S Reuter American Journal of Transplantation 16 (5), 1612-1619 2016

Detection of acute renal allograft rejectionS Reuter, K Tiemann
US Patent App. 14/776,720 2016

Noninvasive imaging of acute renal allograft rejection by ultrasound detection of microbubbles targeted to T-lymphocytes in ratsA Grabner, D Kentrup, M Mühlmeister, H Pawelski, C Biermann, Reuter, K Tiemann
Ultraschall in der Medizin-European Journal of Ultrasound 37 (01), 82-91 2016

Grabner A., Kentrup D., Mühlmeister M., Pawelski H., Biermann C., Bettinger T., Pavenstädt H., Schlatter E.K Tiemann, S Reuter

2016

Soluble Flt-1 links microvascular disease with heart failure in CKDGS Di Marco, D Kentrup, S Reuter, AB Mayer, L Golle, K Tiemann, …Basic research in cardiology 110 (3), 27

2015

Differenzialtherapie bei Risikopatienten mit Vorhofflimmern–Nur ASS, DOAKs, Vorhofohrokkluder?T Lewalter, K Tiemann Der Klinikarzt 44 (S 01), 46-49 2015

Ultrasound-mediated gene delivery of naked plasmid DNA in skeletal muscles: a case for bolus injectionsPG Sanches, M Mühlmeister, R Seip, E Kaijzel, C Löwik, M Böhmer, …Journal of Controlled Release 195, 130-137 2014

Development of an anatomic heart model for the minimally-invasive closure of the left atrial appendageEC Graf, DB Roppenecker, K Tiemann, VD Samper, TC Lueth. 2014 IEEE International Conference on Robotics and Biomimetics (ROBIO 2014 …2014

CD3-MEDIATED CONTRAST-ENHANCED SONOGRAPHY FOR DIAGNOSIS OF ACUTE RENAL ALLOGRAFT REJECTION: P029A Grabner, D Kentrup, M Mühlmeister, H Pawelski, H Pavenstädt, …
Transplant International 27 2014

CD3-Mediated Contrast-Enhanced Sonography For Diagnosis of Rat Renal Allograft Rejection.: Abstract# C1541A Grabner, D Kentrup, M Muehlmeister, H Pawelski, H Pavenstaedt, …Transplantation 98, 327 2014

The endocannabinoid-CB2 receptor axis protects the ischemic heart at the early stage of cardiomyopathyGD Duerr, JC Heinemann, G Suchan, E Kolobara, D Wenzel, C Geisen, …Basic research in cardiology 109 (4), 425 2014

Recommandations on emergency echocardiographyA Hagendorff, K Tiemann, G Simonis, dell’Orto, M. Campo, …KARDIOLOGE 8 (1), 45-64 2014

Empfehlungen zur NotfallechokardiographieA Hagendorff, K Tiemann, G Simonis, MC dell‘Orto, S von Bardeleben Der Kardiologe 8 (1), 45-64 2014

Cardioprotective effects of osteopontin-1 during development of murine ischemic cardiomyopathyGD Duerr, B Mesenholl, JC Heinemann, M Zoerlein, P Huebener, …BioMed research international 2014

Research Article Cardioprotective Effects of Osteopontin-1 during Development of Murine Ischemic CardiomyopathyGD Duerr, B Mesenholl, JC Heinemann, M Zoerlein, P Huebener, …2014

CONTRAST ENHANCED SONOGRAPHY TARGETING T-CELLS FOR DETECTION OF ACUTE RAT RENAL ALLOGRAFT REJECTION: O220A Grabner, D Kentrup, M Muehlmeister, H Pawelski, H Pavenstaedt, …Transplant International 2013

CONTRAST ENHANCED T-CELL TARGETED ULTRASOUND FOR DETECTION OF ACUTE REJECTION IN RAT RENAL TRANSPLANTATION: P148A Grabner, D Kentrup, M Mühlmeister, H Pawelski, H Pavenstädt, …Transplant International 

2013

Comparison of sulfur hexafluoride microbubble (SonoVue)-enhanced myocardial contrast echocardiography with gated single-photon emission computed tomography for detection of …R Senior, A Moreo, N Gaibazzi, L Agati, K Tiemann, B Shivalkar, …Journal of the American College of Cardiology 62 (15), 1353-13612013

Real-time imaging and kinetics measurements of focused ultrasound-induced extravasation in skeletal muscle using SPECT/CTPG Sanches, R Rossin, M Böhmer, K Tiemann, H Grüll Journal of Controlled Release 168 (3), 262-270 2013

Diagnostics and therapy of ischemia in chronic stable angina pectoris. Role of echocardiographyRS von Bardeleben, K Tiemann Herz 38 (4), 334-343 2013

Diagnostik und Therapie der chronischen MyokardischämieRS von Bardeleben, K Tiemann
Herz 38 (4), 334-343 2013

New perspectives in transplantation therapyA Grabner, D Kentrup, M Muehlmeister, H Pawelski, H Pavenstädt, …Nephrology Dialysis Transplantation 28 (suppl_1) 2013

Cardiovascular disease in CKDJS van den Broek, T Hoekstra, C Drechsler, VM Brandenburg, FW Dekker, …
Nephrology Dialysis Transplantation 28 (suppl_1), i11-i12 2013

New perspectives in transplantation therapyV Dimuccio, A Ranghino, E Basso, L Biancone, G Camussi, B Bussolati, …Nephrology Dialysis Transplantation 28 (suppl_1), i72-i72 2013

SOLUBLE FLT-1 CONTRIBUTES TO CARDIOVASCULAR DISEASE IN CKDG Di Marco, S Reuter, D Kentrup, K Tiemann, M Fobker, C Engelbertz, … NEPHROLOGY DIALYSIS TRANSPLANTATION 28, 11-2013

ULTRASOUND-BASED DETECTION OF MICROBUBBLES TARGETED TO T-LYMPHOCYTES AS NON-INVASIV DIAGNOSTIC INVESTIGATION OF ACUTE REJECTION IN DIFFRENT RAT MODELS OF RENAL DESEASEA Grabner, D Kentrup, M Muehlmeister, H Pawelski, H Pavenstaedt, …NEPHROLOGY DIALYSIS TRANSPLANTATION 28, 72-72 2013

Ultrasound-based Diagnosis of acute Renal Transplant Rejection by Antibody-marked Microbubbles and human T-Lymphocytes in a Rat ModelA Grabner, D Kentrup, M Muehlmeister, H Pawelski, H Pavenstaedt, …INTERNIST 54, 49-49 2013

Non-Invasive Imaging of Acute Allograft Rejection by Ultrasound Detection of Microbubbles Targeted to T-Lymphocytes in a Rat Renal Transplantation Model.: Abstract# B869A Grabner, D Kentrup, M Mühlmeister, H Pawelski, H Pavenstädt, …American Journal of Transplantation 13 2013

Quantitative myocardial contrast supine bicycle stress echocardiography for detection of coronary artery diseaseT Miszalski‐Jamka, S Kuntz‐Hehner, K Tiemann, K Karwat, M Kostkiewicz Echocardiography 30 (4), 392-400 2013

Early detection of cardiac involvement of Fabry Disease using 3D speckle tracking analysisC Landgraf, L Ting, K Tiemann, MA Engelen, T Duning, E Brand, …2013

Comparison of sulfur hexafluoride microbubble (SonoVue)-enhanced myocardial echocardiography to single photon emission computerized tomography at rest and vasodilator stress in …R Senior, J Kasprzak, A Moreo, N Gaibazzi, L Agati, K Tiemann, … Circulation 126 (suppl_21), A13517-A13517 2012

Cardiomyocyte-specific deletion of survivin causes global cardiac conduction defectsJW Schrickel, L Lickfett, T Lewalter, K Tiemann, G Nickenig, H Baba, …Basic research in cardiology 107 (6), 1-12 2012

4D phase contrast flow imaging for in-stent flow visualization and assessment of stent patency in peripheral vascular stents–A phantom studyAC Bunck, A Jüttner, JR Kröger, MC Burg, H Kugel, T Niederstadt, …
European journal of radiology 81 (9), e929-e937 2012

Cardiomyopathy Caused by Longterm Treatment with Chloroquine: A Rare Disease or a Rare Diagnosis?(vol 39, pg 1099, 2012)E Toennesmann, I Stroehmann, R Kandolf, H Wolburg, K Strach, …
JOURNAL OF RHEUMATOLOGY 39 (7), 1496-1496 2012

Differentiation of malignant and benign cardiac tumors using 18F-FDG PET/CTK Rahbar, H Seifarth, M Schäfers, L Stegger, A Hoffmeier, T Spieker, …Journal of Nuclear Medicine 53 (6), 856-863 2012

Cardiomyopathy caused by longterm treatment with chloroquine: a rare disease, or a rare diagnosis?E Toennesmann, I Stroehmann, R Kandolf, H Wolburg, K Strach, …The Journal of rheumatology 39 (5), 1099-1103 2012

Cardiomyopathy Caused by Longterm Treatment with Chloroquine: A RareT LEWALTER, KS WOLBURG, F MUSSHOFF, K TIEMANN The Journal of Rheumatology 39 (5), 1099-1103 2012

Transforming growth factor β 1 oppositely regulates the hypertrophic and contractile response to β-adrenergic stimulation in the heartM Huntgeburth, K Tiemann, R Shahverdyan, KD Schlüter, …
PloS one 6 (11), e26628 2011

Exercise-induced adaptations of cardiac redox homeostasis and remodeling in heterozygous SOD2-knockout miceL Richters, N Lange, R Renner, N Treiber, A Ghanem, K Tiemann, …
Journal of Applied Physiology 111 (5), 1431-1440 2011

Cardiomyoplasty improves contractile reserve after myocardial injury in mice: functional and morphological investigations with reconstructive three-dimensional echocardiographyA Ghanem, W Röll, T Bostani, O Dewald, BK Fleischmann, J Stypmann, …Cell transplantation 20 (10), 1621-1628 2011

FGF23 induces left ventricular hypertrophyC Faul, AP Amaral, B Oskouei, MC Hu, A Sloan, T Isakova, OM Gutiérrez, …The Journal of clinical investigation 121 (11) 2011

Histogram-based optical flow for functional imaging in echocardiographyS Schmid, D Tenbrinck, X Jiang, K Schäfers, K Tiemann, J Stypmann International Conference on Computer Analysis of Images and Patterns, 477-485 2011

Cardioprotective effect of calcineurin inhibition in an animal model of renal diseaseGS Di Marco, S Reuter, D Kentrup, L Ting, L Ting, A Grabner, AM Jacobi, …European heart journal 32 (15), 1935-1945 2011

Persistent Eustachian valve, Chiari network and atrial septum aneurysm in adults: association with a patent foramen ovale in Stroke patientsF Landeta, K Boentert, M Ritter, E Bussche, S Hardjanto, MA Engelen, …
EUROPEAN HEART JOURNAL 32, 559-559 2011

Subvalvular hypertrophic calcification of the mitral annulus:[18 F] FDG–PET–CT, MRI, and echocardiography findingsT Persigehl, D Maintz, P Kies, W Heindel, O Schober, K Tiemann, …
Journal of Nuclear Cardiology 18 (2), 368-370. 2011

Echokardiographie fürK Tiemann
RöFo-Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden … 2011

Role of the transcription factor CREB in the vasculature under physiological and pathophysiological conditionsMD Seidl, AK Steingraeber, TMH Sur, L Ting, K Tiemann, S Offermanns, …NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 383, 43-44 2011

Pathological 99mTc-sestamibi myocardial perfusion scintigraphy is independently associated with emerging cardiac events in elderly patients with known or …J Bucerius, AY Joe, E Herder, H Brockmann, K Biermann, H Palmedo, … Acta Radiologica 52 (1), 52-58 2011

NUCLEAR CARDIOLOGY BULLET Subvalvular hypertrophic calcification of the mitral annulus:[18 F] FDG–PET–CT, MRI, and echocardiography findingsT Persigehl, D Maintz, P Kies, W Heindel, O Schober, K Tiemann 2011

Vascular infarction by subcutaneous application of tissue factor targeted to tumor vessels with NGR-peptides: activity and toxicity profileJ Dreischalück, C Schwöppe, T Spieker, T Kessler, K Tiemann, R Liersch, …International journal of oncology 37 (6), 1389-1397 2010

Three-dimensional echocardiography and 153 Sm-EDTMP SPECT/CT in extensive cardiac metastases from osteosarcomaK Tiemann, J Stymann, F Landeta, S Wiebe, M Schäfers, O Schober, … European journal of nuclear medicine and molecular imaging 37 (12), 2406-2406 2010

Significant Association of Female Gender with Lower Degree of Pathological 99m Tc-sestamibi Scintigraphy Results as well as Higher Cardiac-Related Deaths Free Survival in …J Bucerius, AY Joe, E Herder, H Brockmann, MJ Reinhardt, H Palmedo, …Medizinische Klinik 105 (12), 901-909 2010

An ultrasound view on the substrate for incident and recurrent atrial fibrillation in heart failure patientsP Kirchhof, L Fabritz, K Tiemann European journal of heart failure 12 (10), 1019-1020 2010

The scavenger receptor class B type I-deficient, hypomorphic apolipoprotein E-R61 mouse-a new mouse model exhibiting diet-induced occlusive coronary atherosclerosis and …K Tiemann, M Kuhlmann, M Muehlmeister, J Stypmann, T Liu, L Ting, …EUROPEAN HEART JOURNAL 31, 9-9 2010

Total [Beta]-Adrenoceptor Deficiency Results in Cardiac Hypotrophy and Negative InotropyS Lee, S Grafweg, T Schneider, M Jimenez, JP Giacobino, A Ghanem, … Physiological research 59 (5), 679. 2010

Untersuchung zur Anwendbarkeit und Validität der zeitaufgelösten 3D-Phasenkontrastflussmessung zur Flussvisualisierung und-quantifizierung in peripheren GefäßstentsAC Bunck, JR Kröger, A Jüttner, K Tiemann, G Crelier, W Heindel, … RöFo-Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden … 2010

eNOS phosphorylation and translocation are altered in male but not female mice by increased activation of the Gαq proteinC Ruiz-Holst, B Bölck, A Ghanem, K Tiemann, S Brokat, … Canadian journal of physiology and pharmacology 88 (2), 121-129 2010

In vivo SPECT/CT imaging of focused ultrasound induced extravasationP Sanches, R Rossin, M Böhmer, K Tiemann, H Grüll Nuclear Medicine and Biology 6 (37), 722 2010

Signifikante Beziehung zwischen weiblichem Geschlecht und einem niedrigeren Grad pathologischer 99mTc-sestamibi Szintigraphieergebnisse sowie einem höheren Herztod-freien …J Bucerius, AY Joe, E Herder, H Brockmann, MJ Reinhardt, H Palmedo, … Medizinische Klinik-Intensivmedizin und Notfallmedizin 105 (12), 901 2010

Single Shot Quantification of Gas-Filled Microbubbles with UltrasoundJS Praßni, K Storm, T Ropinski, K Tiemann Eurographics Workshop on Visual Computing for Biology and Medicine (VCBM … 2010

Manual to the indication and performance of the echocardiography (vol 4, pg 3, 2009)T Buck, OA Breithardt, L Faber, W Fehske, FA Flachskampf, A Franke, …
Clinical Research In Cardiology 99 (1), 63-63 2010

Functional impact of targeted closed-chest transplantation of bone marrow cells in rats with acute myocardial ischemia/reperfusion injuryA Ghanem, A Ziomka, B Krausgrill, K Schenk, C Troatz, T Miszalski-Jamka, …Cell transplantation 18 (12), 1289-1297 2009

Circadian Short-term Heart Rate Variability Deteriorates in Beta Knock Out MiceJO Schwab, P Paschenda, M Schlosser, K Tiemann, G Nickenig, …Circulation 120 (suppl_18), S647-S648 2009

Myocardial contrast echocardiography enhances long-term prognostic value of supine bicycle stress two-dimensional echocardiographyT Miszalski-Jamka, S Kuntz-Hehner, H Schmidt, D Peter, …
Journal of the American Society of Echocardiography 22 (11), 1220-1227. 2009

Lack of gelsolin promotes perpetuation of atrial fibrillation in the mouse heartJW Schrickel, K Fink, R Meyer, C Grohé, F Stoeckigt, K Tiemann, …Journal of interventional cardiac electrophysiology 26 (1), 3-10
 2009

Ultrasound mediated gene silencing with short-hairpin RNACT Chin, CS Hall, A Ghanem, K Tiemann
2009 IEEE International Ultrasonics Symposium, 1784-1787 2009

Focused ultrasound-induced stimulation of microbubbles augments site-targeted engraftment of mesenchymal stem cells after acute myocardial infarctionA Ghanem, C Steingen, F Brenig, F Funcke, ZY Bai, C Hall, CT Chin, … Journal of Molecular and Cellular Cardiology 47 (3), 411-418 2009

Targeted ultrasound-mediated delivery of nanoparticles: on the development of a new HIFU-based therapy and imaging deviceR Seip, CT Chin, CS Hall, BI Raju, A Ghanem, K Tiemann IEEE transactions on biomedical engineering 57 (1), 61-70 2009

Hemodynamic variables during stress testing can predict referral to early catheterization but failed to show a prognostic impact on emerging cardiac events in patients aged 70 …J Bucerius, AY Joe, E Herder, H Brockmann, K Biermann, H Palmedo, … The international journal of cardiovascular imaging 25 (6), 569-579 2009

Impact of previous myocardial infarction on the incremental value of myocardial contrast to two-dimensional supine bicycle stress echocardiography in evaluation of coronary …T Miszalski-Jamka, S Kuntz-Hehner, H Schmidt, K Miszalski-Jamka, … International journal of cardiology 136 (1), 47-55 2009

Ultrasound triggered image-guided drug deliveryMR Böhmer, AL Klibanov, K Tiemann, CS Hall, H Gruell, OC Steinbach European journal of radiology 70 (2), 242-253 2009

S1642 New Tools for In Vivo Imaging of Murine DSS-Colitis-Mrp14-Directed Fluorescence-Mediated Molecular Tomography (FMT) and High-Resolution Ultrasound ImagingD Bettenworth, F Hasenberg, M Eisenblaetter, K Tiemann, J Heidemann, … Gastroenterology 136 (5), A-240-A-241 2009

An Unusual Cause for Recurrent Syncope in a Female Adult with LEOPARD SyndromeC Hammerstingl, A Ghanem, K Tiemann Echocardiography 26 (5), 596-597 2009

Normal impulse propagation in the atrioventricular conduction system of Cx30. 2/Cx40 double deficient miceJW Schrickel, MM Kreuzberg, A Ghanem, JS Kim, M Linhart, R Andrié, … Journal of molecular and cellular cardiology 46 (5), 644-652 2009

Echocardiographic assessment of global left ventricular function in miceJ Stypmann, MA Engelen, C Troatz, M Rothenburger, L Eckardt, … Laboratory Animals 43 (2), 127-137 2009

Manual zur indikation und durchführung der echokardiographieT Buck, OA Breithardt, L Faber, W Fehske, FA Flachskampf, A Franke, … Clinical research in cardiology supplements 4 (1), 3-51 2009

Gone with the flow: percutanous retrieval of a migrated wallstent trapped in the right ventricleA Ghanem, K Tiemann, G Nickenig European heart journal 30 (6), 717-717 2009

Manual for the indication and execution of echocardiographyT Buck, OA Breithardt, L Faber, W Fehske, FA Flachskampf, A Franke, … Clinical Research in Cardiology Supplements 4 (SUPPL. 1), 1-2 2009

Detection of coronary artery disease with perfusion stress echocardiography using a novel ultrasound imaging agent: two Phase 3 international trials in comparison with …R Senior, M Monaghan, ML Main, JL Zamorano, K Tiemann, L Agati, … European Journal of Echocardiography 10 (1), 26-35 2009

Frühzeitiger kombinierter Einsatz von Revaskularisation und intraaortaler Ballon-Gegenpulsation bei kardiogenem Schock im Rahmen eines akuten MyokardinfarktsRP Andrié, L Lickfett, D Skowasch, K Tiemann, S Waßmann, T Lewalter, … Intensivmedizin und Notfallmedizin 45 (8), 463-470 2008

Ultrasound-induced Stimulation Of Microbubbles Augments And Targets Myocardial Engraftment Of Mesenchymal Stem Cells In VivoA Ghanem, C Steingen, F Brenig, ZY Bai, C Hall, CT Chin, G Nickenig, …
Circulation 118 (suppl_18), S_381-S_381 2008

Sex-specific pathways in early cardiac response to pressure overload in miceH Witt, C Schubert, J Jaekel, D Fliegner, A Penkalla, K Tiemann, … Journal of molecular medicine 86 (9), 1013 2008

Accurate detection of coronary artery disease by echocardiography using perflubutane polymer microspheres, a novel contrast agent: Comparison with nuclear perfusion imaging in …R Senior, M Zabalgoitia, M Monaghan, M Main, JL Zamorano, K Tiemann, …HEART 94, A20-A20 2008

Feasibility of 18 F-fluoromethylcholine PET/CT for imaging of vessel wall alterations in humans—first resultsJ Bucerius, J Schmaljohann, I Böhm, H Palmedo, S Guhlke, K Tiemann, … European journal of nuclear medicine and molecular imaging 35 (4), 815-820 2008

Quantitation of Myocardial Borderzone Using Reconstructive 3-D Echocardiography After Chronic Infarction in Rats—Incremental Value of Low-Dose DobutamineA Ghanem, C Troatz, N Elhafi, O Dewald, C Heeschen, G Nickenig, … Ultrasound in medicine & biology 34 (4), 559-566 2008

Survivin determines cardiac function by controlling total cardiomyocyte numberB Levkau, M Schafers, J Wohlschlaeger, K von Wnuck Lipinski, P Keul, … Circulation 117 (12), 1583-1593 2008

Real-time high-resolution compound imaging allows percutaneous initiation and surveillance in an orthotopic murine pancreatic cancer modelC Ziske, K Tiemann, T Schmidt, S Nagaraj, A Märten, V Schmitz, … Pancreas 36 (2), 146-152 2008

The conditional connexin43G138R mouse mutant represents a new model of hereditary oculodentodigital dysplasia in humansR Dobrowolski, P Sasse, JW Schrickel, M Watkins, JS Kim, M Rackauskas, …
Human molecular genetics 17 (4), 539-554 2008

High-resolution myocardial stress perfusion at 3 T in patients with suspected coronary artery diseaseC Meyer, K Strach, D Thomas, H Litt, CP Nähle, K Tiemann, U Schwenger, …European radiology 18 (2), 226-233 2008

Fr hzeitiger kombinierter Einsatz von Revaskularisation und intraaortaler Ballon-Gegenpulsation bei kardiogenem Schock im Rahmen eines akuten MyokardinfarktsRP Andri , L Lickfett, D Skowasch, K Tiemann, S Wa mann, T Lewalter, … Intensivmedizin und Notfallmedizin 45 (8), 463-470 2008

Resolution of refractory ascites after transcoronary septal ablation for hypertrophic obstructive cardiomyopathy in a cirrhotic patientA Höblinger, F Weinberger, K Tiemann, G Nickenig, T Sauerbruch, …
Zeitschrift für Gastroenterologie 46 (01), P5_19 2008

Toll-like receptor 4 deficiency: smaller infarcts, but nogain in functionSC Kim, A Ghanem, H Stapel, K Tiemann, P Knuefermann, A Hoeft, … BMC physiology 7 (1), 1-10 2007

Replacement of connexin43 by connexin26 in transgenic mice leads to dysfunctional reproductive organs and slowed ventricular conduction in the heartE Winterhager, N Pielensticker, J Freyer, A Ghanem, JW Schrickel, JS Kim, … BMC developmental biology 7 (1), 1-14 2007

Transmigration and invasion of mesenchymal stem cells: 90.C Steingen, F Brenig, A Ghanem, K Tiemann, W Bloch Regenerative Medicine 2 (6) 2007

Enhanced heterogeneity of myocardial conduction and severe cardiac electrical instability in annexin A7-deficient miceJW Schrickel, K Brixius, C Herr, CS Clemen, P Sasse, K Reetz, C Grohé, … Cardiovascular research 76 (2), 257-268 2007

Accurate detection of coronary artery disease by echocardiography using perflubutane polymer microspheres, a novel contrast agent: comparison with nuclear perfusion imaging in …R Senior, M Zabalgoitia, M Monaghan, M Main, JL Zamorano, K Tiemann, … Circulation 116 (suppl_16), II_546-II_546 2007

Function of Connexin30. 2 and Connexin40 in AV-Nodal ConductionJW Schrickel, M Kreuzberg, A Ghanem, C Troatz, K Tiemann, G Nickenig, … Circulation 116 (suppl_16), II_87-II_87 2007

Female gender is independently associated with a lower degree of myocardial perfusion defects as assessed by TC-99m Sestamibi myocardial perfusion scintigraphy as well as …J Bucerius, AY Joe, E Herder, K Biermann, H Brockmann, S Ezziddin, … EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 34, S181-S181 2007

Modulation of the AV-nodal conduction by Connexin40 and Connexin30. 2JW Schrickel, M Kreuzberg, A Ghanem, K Tiemann, G Nickenig, … EUROPEAN HEART JOURNAL 28, 3-4 2007

Potential risks of bone marrow cell transplantation into infarcted heartsM Breitbach, T Bostani, W Roell, Y Xia, O Dewald, JM Nygren, JWU Fries, … Blood, The Journal of the American Society of Hematology 110 (4), 1362-1369 2007

Call for echo-contrastK Tiemann
The international journal of cardiovascular imaging 23 (4), 491-491 2007

Real time myocardial contrast echocardiography during supine bicycle stress and continuous infusion of contrast agent. Cutoff values for myocardial contrast replenishment …T Miszalski‐Jamka, S Kuntz‐Hehner, H Schmidt, C Hammerstingl, … Echocardiography 24 (6), 638-648 2007

Triggered replenishment imaging reduces variability of quantitative myocardial contrast echocardiography and allows assessment of myocardial blood flow reserveA Ghanem, AN DeMaria, S Lohmaier, MA El‐Sayed, M Strachan, … Echocardiography 24 (2), 149-158 2007

Durch ultraschallbasierte Mikrobläschenwiederanflutungskinetikmessungen können nichtinvasiv Durchblutungsveränderungen der Nierenrinde bei Zirrhotikern festgestellt werdenC Rabe, J Heller, A Ghanem, L Schmidt, HU Klehr, K Tiemann, … Zeitschrift für Gastroenterologie 45 (01), A5_02 2007

Detection of coronary arteries and evaluation of anastomoses with a commercially available 15-MHz, broadband, linear array transducerW Schiller, H Rudorf, K Tiemann, C Probst, F Mellert, A Welz
HEART SURGERY FORUM 10 (5), 279 2007

Imaging in Basic Science. Mouse‐ECHO: From Bedside to Bench: Part IK Tiemann
Echocardiography 23 (10), 890-890 2006

Echocardiographic assessment of left ventricular mass in neonatal and adult mice: accuracy of different echocardiographic methodsA Ghanem, W Röll, T Hashemi, O Dewald, PC Djoufack, KB Fink, …
Echocardiography 23 (10), 900-907 2006

Cardiac morphogenetic defects and conduction abnormalities in mice homozygously deficient for connexin40 and heterozygously deficient for connexin45O Krüger, S Maxeiner, JS Kim, HVM van Rijen, JMT de Bakker, D Eckardt, … Journal of molecular and cellular cardiology 41 (5), 787-797 2006

MICROBUBBLE FLASH REPLENISHMENT KINETICS INDICATE DECREASED CORTICAL KIDNEY PERFUSION IN CIRRHOTICS: 725L Schmidt, C Rabe, A Ghanem, J Heller, H Klehr, K Tiemann, …
Hepatology 44 2006

Persistence of iatrogenic atrial septal defect after pulmonary vein isolation—an underestimated risk?C Hammerstingl, L Lickfett, KM Jeong, C Troatz, JA Wedekind, K Tiemann, … American heart journal 152 (2), 362. e1-362. e5 2006

TGF-beta differentially regulates the hypertrophic and contractile responsiveness to catecholamines in the heartE Caglayan, M Huntgeburth, ML Gross, K Amann, K Tiemann, A Ghanem, … EUROPEAN HEART JOURNAL 27, 473-473 2006

Age and gender related reference values for transthoracic Doppler-echocardiography in the anesthetized CD1 mouseJ Stypmann, MA Engelen, C Epping, HVM van Rijen, P Milberg, C Bruch, …
The international journal of cardiovascular imaging 22 (3), 353-362 2006

Paroxysmal atrial flutter caused by cardiac lymphomaM Linhart, L Lickfett, C Hammerstingl, K Tiemann, G Nickenig, T Lewalter Pacing and clinical electrophysiology 29 (6), 682-684 2006

Biliary metal stents and air embolism: a note of cautionC Rabe, Z Balta, U Wüllner, J Heller, C Hammerstingl, K Tiemann, …Endoscopy 38 (06), 648-650 2006

P3-15: Electrocardiographic alterations and changes in heart rate and short term heart rate variability in neonatal mice expressing connexin 31 instead of connexin 43JO Schwab, A Ghanem, Q Zheng-Fischhofer, K Willecke, K Tiemann Heart Rhythm 3 (5), S182-S183 2006

Connexin30. 2 containing gap junction channels decelerate impulse propagation through the atrioventricular nodeMM Kreuzberg, JW Schrickel, A Ghanem, JS Kim, J Degen, …
Proceedings of the National Academy of Sciences 103 (15), 5959-5964 2006

Connexin30. 2 containing gap junction channels decelerate AV-nodal conductionJW Schrickel, M Kreuzberg, A Ghanem, JS Kim, J Degen, K Tiemann, …
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 47 (4), 1A-1A 2006

Significant low-voltage ECG and impaired systolic cardiac function in neonatal mice expressing Connexin 31 instead of 43A Ghanem, QY Zheng-Fischhofer, JO Schwab, JS Kim, M Kibschull, …
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 47 (4), 1A-1A 2006

Persistence of iatrogenic atrial septal defect after pulmonary vein isolation with transseptal puncture-an underestimated risk?C Hammerstingt, KM Jeong, C Troatz, K Tiemann, B Luederitz, L Lickfett
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 47 (4), 29A-30A 2006

Connexin31 cannot functionally replace connexin43 during cardiac morphogenesis in miceQ Zheng-Fischhöfer, A Ghanem, JS Kim, M Kibschull, G Schwarz, … Journal of cell science 119 (4), 693-701 2006

Ruptured sinus of Valsalva aneurysm in two patients with subarterial ventricular septal defectU Doll, U Herberg, K Tiemann, J Schirrmeister, C Bernhardt, W Köhler, … Clinical research in cardiology 95 (2), 127-131 2006

Open access echocardiography-Guide or expense factor?K Tiemann
The international journal of cardiovascular imaging 22 (1), 27 2006

Dobutamin-Stress-MRT zur Primärdiagnostik der koronaren Herzerkrankung: Evaluierung der B-SSFP-Technik in Kombination mit paralleler BildgebungC Meyer, K Strach, CP Nähle, M Hackenbroch, A Schmiedel, K Tiemann, … RöFo-Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden …2006

Long-term fate of left atrial thrombi and incidence of cerebral embolism under continuous anticoagulation therapy; MR-tomographische Evaluation der Inzidenz zerebraler Embolien …K Strach, C Meyer, M Hackenbroch, H Schild, T Sommer, K Tiemann, … RoeFo-Fortschritte auf dem Gebiete der Roentgenstrahlen und der Neuen … 2005

Long-term fate of left atrial thrombi and incidence of cerebral embolism under continuous anticoagulation therapyK Strach, C Meyer, M Hackenbroch, K Tiemann, J Haase, L Pizulli, … RoFo: Fortschritte auf dem Gebiete der Rontgenstrahlen und der … 2005

MR-tomographische Evaluation der Inzidenz zerebraler Embolien bei Patienten mit Vorhofflimmern und linksatrialen ThrombenK Strach, C Meyer, M Hackenbroch, K Tiemann, J Haase, L Pizulli, …
RöFo-Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden …2005

Function of connexin45 in the adult mouse heartJW Schrickel, S Maxeiner, M Linhart, A Ghanem, K Tiemann, B Luderitz, …CIRCULATION 112 (17), U245-U245 2005

Latrogenic atrial septal defect after pulmonary vein isolation-an underestimated risk?C Hammerstingl, C Troatz, T Lewalter, B Luederitz, K Tiemann EUROPEAN HEART JOURNAL 26, 597-597 2005

Lack of gelsolin promotes perpetuation of atrial fibrillation in the mouse heartJ Schrickel, K Fink, R Meyer, C Grohe, K Tiemann, H Bielik, B Luederitz, … EUROPEAN HEART JOURNAL 26, 663-663 2005

Low-voltage ECG and impaired systolic cardiac function in neonatal mice expressing Connexin 31 instead of 43A Ghanem, Q Zheng-Fischhofer, JO Schwab, JS Kim, G Schwarz, … EUROPEAN HEART JOURNAL 26, 595-595 2005

Truncation of the C-terminal region of Connexin43 leads to QT-prolongation and ST-elevation in neonatal miceA Ghanem, K Maass, JW Schrickel, M Linhart, T Lewalter, B Luderitz, … EUROPEAN HEART JOURNAL 26, 595-595 2005

3D motion adapted gating (3D MAG): a new navigator technique for accelerated acquisition of free breathing navigator gated 3D coronary MR-angiographyM Hackenbroch, K Nehrke, J Gieseke, C Meyer, K Tiemann, H Litt, … European radiology 15 (8), 1598-1606 2005

Gold‐Tip Electrodes—A New “Deep Lesion” Technology for Catheter Ablation? In Vitro Comparison of a Gold Alloy Versus Platinum–Iridium Tip Electrode Ablation CatheterT Lewalter, A Bitzen, S WURTZ, Ph. D, R BLUM, Ph. D, …Journal of cardiovascular electrophysiology 16 (7), 770-772 2005

MRT-Vitalitätsdiagnostik mittels einer kontrastverstärkten 3D-Sequenz kombiniert mit paralleler Bildgebung (SENSE) im Nachweis von MyokardinfarktenAS Schmiedel, M Hackenbroch, C Meyer, K Tiemann, HH Schild, … RöFo-Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden …2005

Iatrogenic atrial septal defect after pulmonary vein isolation-an underestimated risk?C Hammerstingl, T Lewalter, C Troatz, B Lüderitz, K Tiemann Heart Rhythm 2 (5), S233 2005

3D Motion Adapted Gating: Eine neue Navigatortechnik zur Verkürzung der Messzeit bei der MR-KoronarangiographieM Hackenbroch, C Meyer, G Beck, K Nehrke, J Gieseke, A Yang, …
RöFo-Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden …2005

3D motion adapted gating: a new navigator technique to shorten the acquisition time for coronary MRAM Hackenbroch, C Meyer, G Beck, K Nehrke, J Gieseke, A Yang, …RoFo: Fortschritte auf dem Gebiete der Rontgenstrahlen und der …2005

3D Motion Adapted Gating: a new navigator technique to shorten the acquisition time for coronary MRA; 3D Motion Adapded Gating: Eine neue Navigatortechnik zur Verkuerzung der …M Hackenbroch, C Meyer, H Schild, T Sommer, G Beck, K Nehrke, …RoeFo-Fortschritte auf dem Gebiete der Roentgenstrahlen und der Neuen …2005

Sustained atrial fibrillation and enhanced susceptibility to ventricular tachycardia in the annexin A7-deficient mouseJW Schrickel, C Herr, CS Clemen, M Rick, C Grohe, R Meyer, K Tiemann, …
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 45 (3), 122A-122A 2005

Abnormalities of epidermis, heart and ovaries in mice expressing C-terminally truncated Connexin43 proteinK Maass, A Ghanem, JS Kim, M Saathoff, S Urschel, G Kirfel, R Grummer, …
MOLECULAR BIOLOGY OF THE CELL 15, 309A-309A 2004

QT-Prolongation and ST-elevation in neonatal mice lacking the C-terminal region of Connexin43A Ghanem, K Maass, JS Kim, S Urschel, M Linhart, JW Schrickel, …CIRCULATION 110 (17), 151-152 2004